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Choose from 50,000 certified project topics & complete materials from all departments. With software/App development and Device construction for Science & Engineering.
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I-[human IgG] were to cross-react with the CEA or GDF15 beads, this could be distinguished from true CEA or GDF15 signal on the basis of the fluorescence color). Nonetheless, a critical first step was to confirm that these three biomarkers could indeed be multiplexed without cross-reaction or interference among the various capture and detection agents. As a first step, since recombinant protein st
1
I-[human IgG] were to cross-react with the CEA or GDF15 beads, this could be distinguished from true CEA or GDF15 signal on the basis of the fluorescence color). Nonetheless, a critical first step was to confirm that these three biomarkers could indeed be multiplexed without cross-reaction or interference among the various capture and detection agents. As a first step, since recombinant protein st
1
And scoring method, individually, CEA, GDF15 and the p53 TAA were 21 , 38 and 11 sensitive and 98 , 100 and 100 specific, respectively. Composite sensitivity and specificity of all 3 biomarkers in the multiplexed assay was 54 and 98 , respectively and biomarker overlap (or lack thereof) is shown in the Venn Diagram in Figure 5B. Notably, while partial redundancy is observed, each biomarker de
1
And scoring method, individually, CEA, GDF15 and the p53 TAA were 21 , 38 and 11 sensitive and 98 , 100 and 100 specific, respectively. Composite sensitivity and specificity of all 3 biomarkers in the multiplexed assay was 54 and 98 , respectively and biomarker overlap (or lack thereof) is shown in the Venn Diagram in Figure 5B. Notably, while partial redundancy is observed, each biomarker de
1
And scoring method, individually, CEA, GDF15 and the p53 TAA were 21 , 38 and 11 sensitive and 98 , 100 and 100 specific, respectively. Composite sensitivity and specificity of all 3 biomarkers in the multiplexed assay was 54 and 98 , respectively and biomarker overlap (or lack thereof) is shown in the Venn Diagram in Figure 5B. Notably, while partial redundancy is observed, each biomarker de
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